Contributions of nucleus accumbens dopamine to cognitive flexibility
نویسندگان
چکیده
منابع مشابه
Phasic Nucleus Accumbens Dopamine Encodes
JONATHAN SUGAM: Phasic nucleus accumbens dopamine encodes risk-based decision making behavior (Under the direction of Regina M. Carelli) When deciding to act organisms must correctly evaluate the costs and benefits of action selection in order to optimize resources. Several factors influence the evaluation of reward value including the behavioral cost, the delay to, probability of, and magnitud...
متن کاملRelationship of Dopamine of the Nucleus Accumbens with Intra-infralimbic Apomorphine Microinjection
Objective(s): The dopamine level of the nucleus accumbens changes during some stereotyped behaviors. To study dopamine level of the nucleus accumbens in intra infralimbic apomorphine-induced climbing, microdialysis probes were implanted into the nucleus accumbens shell of male Sprague Dawley rats weighting 275–400 g. Materials and Methods: The rats were divided into two groups (apomorphine ...
متن کاملrelationship of dopamine of the nucleus accumbens with intra-infralimbic apomorphine microinjection
objective(s): the dopamine level of the nucleus accumbens changes during some stereotyped behaviors. to study dopamine level of the nucleus accumbens in intra infralimbic apomorphine-induced climbing, microdialysis probes were implanted into the nucleus accumbens shell of male sprague dawley rats weighting 275–400 g. materials and methods: the rats were divided into two groups (apomorphine an...
متن کاملCholinergic depletion in nucleus accumbens impairs mesocortical dopamine activation and cognitive function in rats.
In rats, selective depletion of the cholinergic interneurons in the ventral striatum (nucleus accumbens or N.Acc.) results in heightened behavioural sensitivity to amphetamine and impaired sensorimotor gating processes, suggesting a hyper-responsiveness to dopamine (DA) activity in the N.Acc. We hypothesized that local cholinergic depletion may also trigger distal functional alterations, partic...
متن کاملEncoding of Aversion by Dopamine and the Nucleus Accumbens
Adaptive motivated behavior requires rapid discrimination between beneficial and harmful stimuli. Such discrimination leads to the generation of either an approach or rejection response, as appropriate, and enables organisms to maximize reward and minimize punishment. Classically, the nucleus accumbens (NAc) and the dopamine projection to it are considered an integral part of the brain's reward...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Neuroscience
سال: 2018
ISSN: 0953-816X,1460-9568
DOI: 10.1111/ejn.14152